Trisomy 21, 3D rendering of simian crease Daniel Margulies, MD Article Published: May 24, 2002 Buenos Aires, Argentina This is 3rd trimester fetus with trisomy 21. The 3D rendering depicts the simian crease and is easier to obtain than 2D images (see Skeletal findings in aneuploidy) Discussion Board Start a discussion about this article Add bookmark Bookmarked